Mitochondrial dysfunction in obesity
نویسندگان
چکیده
منابع مشابه
Mitochondrial Dysfunction in Obesity and Diabetes
dysfunction and insulin resistance; most importantly in hepatocytes, myocytes, and adipocytes. Type 2 diabetes is well known to be a progressive disorder characterized by deteriorating capacity for insulin release and action. Both defects are recognizable early on and present even in non-diabetic offspring of patients with type 2 diabetes. However, there is general consensus that insulin sensit...
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متن کامل[Hypothalamic dysfunction in obesity].
Obesity, defined as abnormal or excessive fat accumulation that may impair life quality, is one of the major public health problems worldwide. It results from an imbalance between food intake and energy expenditure. The control of energy balance in animals and humans is performed by the central nervous system (CNS) by means of neuroendocrine connections, in which circulating peripheral hormones...
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Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system that inflammation, demyelination, oligodendrocyte loss, gliosis, axonal injury and neurodegeneration are the main histopathological hallmarks of the disease. Although MS was classically thought as a demyelinating disease, but axonal injury occurs commonly in acute inflammatory lesions. In MS mi...
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ژورنال
عنوان ژورنال: Current Opinion in Endocrinology, Diabetes and Obesity
سال: 2010
ISSN: 1752-296X
DOI: 10.1097/med.0b013e32833c3026